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Improving target volume delineation for 3D image-based dosimetry in PRRT

Emiliano Spezi molecular radiotherapy NET neuroendocrine radionuclide Salvatore Berenato

Peptide receptor radionuclide therapy (PRRT) using radiolabelled somatostatin analogues is currently the most effective molecular radiotherapy (MRT) treatment for patients who suffer from neuroendocrine tumours (NET) with metastasised disease. In PRRT the treatment is systemic and the most frequent treatment protocol is to administer 7.4GBq of Lu-177 up to four times with a six to 10-week interval between each administration. The cumulative absorbed dose that can be administered to the tumour is limited by the unavoidable irradiation of the organs at risk (OAR), such as kidneys and bone marrow.

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Exploring factors influencing TVUS acceptance among ethnic minority and white British women in the UK

Transvaginal ultrasound (TVUS) is a pivotal diagnostic tool in gynaecology, offering high accuracy in detecting pelvic pathologies. Despite its clinical efficacy, TVUS faces significant acceptance barriers, particularly among ethnic minority women in the UK. This mixed-methods study investigates cultural, informational and gender-based factors influencing TVUS acceptance across diverse ethnic groups. Twelve women from varied ethnic […]

Nargis Begum

Nargis Begum

Royal Stoke University Hospital

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The ultrasound appearances of non-tubal ectopic pregnancies

This article provides a comprehensive overview of the ultrasound characteristics of non-tubal ectopic pregnancies, which account for approximately five per cent of all ectopic pregnancies. Unlike tubal ectopics, non-tubal variants pose greater diagnostic challenges and carry increased risks of morbidity and mortality due to delayed recognition. The author emphasises the importance of a systematic transvaginal […]

Naomi Page

Dr Naomi Page

The Hurley Group, London

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From nuclear medicine to molecular imaging in 40 years

The history of nuclear medicine as a clinical discipline roughly maps on to my lifetime, and that of radiology as a whole on to the lives of my older relatives.My grandmother’s birth (1898) coincides with the Curies’ first isolation of radium, and my mother’s (1936) with the first human studies with cyclotron-produced radionuclides, sodium-24 and […]

Prof Phil Blower

Professor Phil Blower

King’s College London

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