Molecular medicine imaging of neuroendocrine tumours

Author(s): Andrew Farnworth, Dr Emmanouil Panagiotidis

Hospital: Royal Liverpool University Hospital

Reference: RAD Magazine, 43, 503, 13-14


Neuroendocrine tumours (NETs) are a diverse, highly heterogeneous group of neoplasms derived from endocrine cells found in the neural crest. NETs typically display endocrine metabolism and slow growth, while displaying a wide range of presentations and clinical symptoms. Demonstrating typically small lesions, with varying anatomical localisation, diagnosis is typically in the advanced stages of tumour development. Molecular medicine provides a unique role in both the diagnosis and treatment of NETs.

The diagnosis of NET is dependent upon clinical features, raised tumour biomarkers within the blood and urine, imaging of primary tumours and/or sites of metastasis and histopathologic results from tissue samples.

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