Home / SNMMI

SNMMI

Real-world results confirm benefit of PSMA therapy for prostate cancer

Prostate-specific membrane antigen (PSMA)-targeted radiopharmaceutical therapy is safe and effective for patients with metastatic castration-resistant prostate cancer (mCRPC) in routine clinical practice, consistent with outcomes from the landmark VISION trial. An analysis of outcomes from a French early-access program, the largest real-world cohort of patients studied to date, confirms the benefit-risk profile of the therapy, […]

Molecular imaging demonstrates promise for predicting complete pathologic response in HER2-positive breast cancer

Molecular imaging with 68Ga-HER2 PETCT may provide an early, targeted measure of how well treatment is working in patients with HER2-positive breast cancer. According to new research published in the October issue of The Journal of Nuclear Medicine, 68Ga-HER2 PETCT can detect changes in HER2-positive breast cancer after only two cycles of neoadjuvant treatment, enabling […]

Proven radiotracer highly effective in detecting rare, aggressive kidney cancer

Renal medullary carcinoma (RMC) demonstrates strong uptake of the radiotracer 18F-FDG, distinguishing it from other types of kidney cancer which often have more variable uptake. 18F-FDG PETCT was found to be highly effective even after systemic treatment and detected additional metastases missed by conventional anatomic imaging, providing a more complete picture of how far the […]

PSMA PETCT-targeted biopsy improves detection of clinically significant prostate cancer

PSMA PETCT-targeted biopsy detects more clinically significant prostate cancer than systematic biopsy alone in men whose MRI findings are negative or inconclusive yet have persistent clinical risk factors. According to new research published in the September issue of The Journal of Nuclear Medicine, combining the two biopsy approaches is even more effective, nearly doubling the […]

PETMR improves presurgical lesion detection in paediatric epilepsy

In children with difficulty-to-diagnose epilepsy, PETMR can pinpoint areas of the brain responsible for seizures, even when MRI scans are negative or inconclusive. A new study of a large paediatric cohort, including children younger than six years old, found that combining PETMR findings with EEG results and a structured presurgical evaluation improved the identification of […]

Novel PETMR approach improves detection of endometriosis in difficult-to-assess areas

A new PETMR technique that targets fibroblast activation protein (FAP) overexpressed in endometriosis is more effective at identifying lesions than conventional imaging. According to new research published in the August issue of The Journal of Nuclear Medicine, this approach was particularly effective in regions of the pelvis and abdomen that are typically difficult to image. By […]

Next generation theranostic pair offers new strategy to detect and treat metastatic kidney cancer

A newly developed radiotheranostic pair, 68Ga/177Lu-NYM096, can identify tumors and effectively deliver targeted radiotherapy to patients with metastatic clear cell renal cell carcinoma (ccRCC). Using a small molecule compound, the new approach helps to mitigate toxicity issues common with treatment, offering a safe and feasible strategy for those with end-stage disease. This research was published in the September issue of […]

Brain metabolism predicts survival in advanced non–small cell lung cancer patients

Low brain metabolism as measured from ¹⁸F-FDG PETCT is associated with higher mortality in patients with advanced non–small cell lung cancer (NSCLC), according to new research published in the July issue of The Journal of Nuclear Medicine. Incorporating brain ¹⁸F-FDG uptake alongside clinical, tumour, and biological data improved prediction of overall survival, providing physicians with valuable […]