68Ga-PSMA PETCT in the management of patients with newly diagnosed prostate cancer

Prostate cancer is the most commonly diagnosed malignancy in men in the UK and the statistics look unfavourable at first glance. According to Cancer Research UK and Prostate Cancer UK, there are just short of 50,000 new prostate cancer cases diagnosed each year in the country, while the yearly number of deaths had reached an all-time high of more than 12,000 in 2017. Moreover, one in eight men are expected to develop prostate cancer in their lifetime, with double the risk for black men, and prostate cancer is expected to be the most common cancer overall by 2030. However, there is also a silver lining, with statistics showing “a much-improved” chance of survival for a man diagnosed in 2020 in comparison to a man diagnosed 10 years ago. This is partly due to the advances in diagnostic imaging and the implementation of more effective diagnostic pathways, including PET imaging with radiolabelled PSMA tracers.

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