The enigmatic breast microcalcification

Author(s): Professor Keith Rogers, Professor Iain Lyburn

Hospital: Cranfield University, Gloucestershire Hospitals NHS Foundation Trust

Reference: RAD Magazine, 49, 572, 9-10


Microcalcifications are a familiar feature within mammographic examination of breast tissues. They are radiologically detected in approximately 80% of breast cancers, although the prevalence in breast tissues is very likely to be significantly greater. They are frequently the only radiological sign that indicates the presence of malignancy. Perhaps previously viewed as simply the end product of a pathological process, questions such as what physiological conditions give rise to them, what their chemical make-up is and whether they have any clinical significance are currently being addressed by several research groups worldwide.

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