Overcoming tumour hypoxia
Cancer occurs as a result of genetic changes and the uncontrolled proliferation of abnormal cells that escape normal homeostatic control mechanisms. As tumour growth outstrips blood supply, cells become hypoxic and the decreased oxygen levels stimulate responses to maximise the chance of cell survival. These biological responses to hypoxia promote aggressive features in tumour cells. […]
Professor Catharine West, Professor Kaye Williams
The University of Manchester, The Christie NHS Foundation Trust