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September 11, 2026

The deteriorating patient in nuclear medicine: anaphylaxis, acute coronary syndrome and hypoglycaemia

Nuclear medicine is often seen as calm, controlled and procedural. Yet deterioration does not wait for the patient to reach a ward, emergency department or arrest team. It may begin after a radiopharmaceutical, contrast agent or adjunct medicine; during stress testing; in a corridor; or in a fasting diabetic patient sitting quietly in the waiting […]

Robin Mark McDade

NHS Greater Glasgow and Clyde

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September 11, 2026

From beta to alpha: understanding the next generation of radiopharmaceutical therapies

Radiopharmaceutical innovation is accelerating, with multiple promising agents approved or in development that have the potential to reshape the cancer treatment landscape. This article provides a clear, clinician-focused overview of where the field currently stands and where it is heading, for an audience increasingly likely to encounter these therapies in their practice. The article outlines […]

Dr Juliana Maynard

Medicines Discovery Catapult

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April 14, 2026

From nuclear medicine to molecular imaging in 40 years

The history of nuclear medicine as a clinical discipline roughly maps on to my lifetime, and that of radiology as a whole on to the lives of my older relatives.My grandmother’s birth (1898) coincides with the Curies’ first isolation of radium, and my mother’s (1936) with the first human studies with cyclotron-produced radionuclides, sodium-24 and […]

Professor Phil Blower

King’s College London

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September 15, 2025

Translation of PET radiotracers and innovative analysis methods to the clinic in the era of total body PET

This article provides a comprehensive overview of the evolution and future potential of PET imaging, particularly in the context of total body PET technology. PET has evolved dramatically since its inception in the 1950s, advancing from basic scanners to sophisticated total body PET systems. These innovations, alongside the development of more selective radiotracers, have significantly […]

Professor Adriana Tavares

The University of Edinburgh

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April 28, 2025

Total body PET imaging: the changing radionuclide imaging landscape in the UK

Non-invasive radionuclide imaging has transformed clinical practice through enabling earlier diagnosis than before, more comprehensive staging, and monitoring of disease progression and therapy response. The quantitative nature of PET and widespread availability of standard radiopharmaceuticals, in particular [18F]FDG, have contributed to PET’s success. However, until recently, in order to capture information ‘from eyes to thighs’, […]

Professor Alexander Hammers; Dr Samantha Terry

King's College London

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April 28, 2025

An overview of CZT technology

The gamma camera has been a stalwart of nuclear medicine for many years. First described in 1958 by Hal Anger, the gamma camera is still the most used instrument for nuclear medicine imaging studies. While the transition to rotating tomographic SPECT systems and the incorporation of CT for SPECT attenuation correction and localisation has changed […]

Professor John C Dickson

University College London Hospitals NHS Foundation Trust

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October 16, 2024

Motion in myocardial perfusion PET

Myocardial perfusion PET is a well established technique for assessing obstructive coronary artery and coronary microvascular diseases. It has been shown to be superior to SPECT imaging in image quality, prognostic information, scan time and lower radiation dose for both the patient and operators. Through the creation of dynamic images, PET also provides the ability […]

Dr Ian Armstrong

Manchester University NHS Foundation Trust

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October 16, 2024

PSMA PET scanning in practice

Prostate cancer is the second most common cancer in the world, predicted to rise by 15% by 2025, while detection in late stage disease increased from 3.9% to 8.2% over the past decade in the USA. Primary investigations for clinical diagnosis and staging of prostate cancer include blood tests, biopsy and imaging techniques such as […]