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radiotherapy

Dosimetry to improve molecular radiotherapy outcomes

This article explores the critical role of dosimetry in enhancing outcomes for molecular radiotherapy (MRT), a treatment modality that delivers targeted radiation to cancer cells via radiopharmaceuticals. While MRT has grown significantly in the UK over the past two decades, current prescribing practices often rely on fixed activity or weight-based adjustments, which fail to account […]

Matt Aldridge

Dr Matt Aldridge

King's College Hospital, London; Internal Dosimetry User Group

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Molecular radiotherapy in prostate cancer

Molecular radiotherapy (MRT), also known as targeted radionuclide therapy or radioligand therapy, is emerging as a transformative approach in the treatment of prostate cancer, particularly in metastatic and castration-resistant cases. Unlike traditional external beam radiotherapy, MRT delivers targeted radiation internally using radioactive substances that bind to specific tumour markers, minimising damage to healthy tissue and […]

Dr Amy Eccles

Dr Amy Eccles

Imperial College Healthcare NHS Trust

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Set-up errors to patient comfort in radiotherapy – a journey of discovery

Accuracy in positioning and immobilisation is fundamental in radiotherapy to ensure precise delivery of radiation to the intended target while minimising exposure to surrounding healthy tissues. The study and critique of accuracy or set-up errors across anatomical cancer sites is well established and has driven technique development for many years. Although patients positioned for radiotherapy […]

Simon Goldsworthy

The Beacon Centre Radiotherapy, Musgrove Park Hospital

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Calling time on the end of treatment bell following radiotherapy: the CELEBRATE study

In UK radiotherapy departments it has become common practice for patients to be invited to ring a bell at the end of treatment as a form of celebration. The sound resonates through hospital corridors, marking the end of a challenging journey. Yet, this seemingly celebratory act has sparked debate, with some questioning whether it serves […]

Keeley Rigby

Keeley Rigby

Sheffield Hallam University

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An overview of the PROSECCA project

Up to half of prostate cancer patients receive radiotherapy as part of their treatment and, although it is effective at destroying cancerous lesions deep within the body, this comes at the cost of damaging healthy, or normal, tissues. With 78% of prostate cancer patients surviving for 10 years or more, limiting life-changing side effects for […]

Professor Bill Nailon, Dr David Noble, Zhuolin Yang, Sarah Elliot, Alasdair Rutherford, Dr Tony Hallam, Dr George Beckett, Professor Duncan McLaren

Edinburgh Cancer Centre; University of Edinburgh; Beatson West of Scotland Cancer Centre

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Image-guided and adaptive radiotherapy for cervical cancer

The established treatment for locally advanced cervical cancer is chemoradiotherapy with external beam radiotherapy (EBRT) and weekly Cisplatin followed by intrauterine brachytherapy. Radiotherapy for cervix cancer is associated with acute and long-term toxicity to adjacent pelvic organs (bladder, bowel, rectum) as they lie in close proximity to the radiotherapy target volume of the cervix, uterus, […]

Benjamin Thomas, Susan Lalondrelle

Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London

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Adaptive radiotherapy and AI in head and neck cancer

Over 12,000 patients are diagnosed with head and neck cancer across the UK every year. Alcohol and tobacco use have long been established as primary risk factors for the development of these cancers. However, there has been a notable increase in the cases of oropharyngeal cancer in recent years, particularly those linked to the oncogenic […]

Polly Darby, John McLellan, Rafael Moleron

Aberdeen Royal Infirmary

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SABR: the new kid on the block for treatment of ventricular tachycardia?

Sudden cardiac death is responsible for 4-5 million annual deaths worldwide. The primary cause of sudden cardiac death is ventricular tachycardia (VT), a cardiac arrhythmia commonly seen in patients with structural heart disease and impaired ventricular function. Conventional VT treatment approaches include antiarrhythmic drugs (AAD), invasive catheter ablation and implantable cardioverter defibrillators (ICD). While these […]

Daniel Hunnybun, Justin Lee, Stephen Riley, Peter Metherall, Matthew Hatton

Northern General Hospital; Weston Park Cancer Centre

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