The voice of medical imaging and clinical oncology

SABR

SABR: the new kid on the block for treatment of ventricular tachycardia?

Sudden cardiac death is responsible for 4-5 million annual deaths worldwide. The primary cause of sudden cardiac death is ventricular tachycardia (VT), a cardiac arrhythmia commonly seen in patients with structural heart disease and impaired ventricular function. Conventional VT treatment approaches include antiarrhythmic drugs (AAD), invasive catheter ablation and implantable cardioverter defibrillators (ICD). While these […]

Daniel Hunnybun, Justin Lee, Stephen Riley, Peter Metherall, Matthew Hatton

Northern General Hospital; Weston Park Cancer Centre

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Developments in lung SABR

The use of stereotactic ablative radiotherapy (SABR) has expanded in the UK over the past decade. In 2008, the UK SABR Consortium was established to help achieve a consensus in implementing and developing SABR in a safe and managed way. In 2011, the National Radiotherapy Implementation Group (NRIG) report recommended that SABR had become standard […]

Caroline Maguire, Kyle Woods, Dr Crispin Hiley

University College London Hospital; GenesisCare

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Stereotactic radiotherapy for oligometastatic cancer

Patients diagnosed with metastatic cancer are living longer due to advances in both systemic anti-cancer therapies and radiotherapy. Metastases from primary tumours cause morbidity and it is estimated that metastases are responsible for approximately 90% of all cancer deaths. The concept of oligometastatic disease (OMD) was first proposed in a seminal paper in 1995 by […]

Dr Emma Doyle, Dr Iain Phillips, Donna Burns

Edinburgh Cancer Centre, University of Edinburgh

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Abdominal compression evaluation for abdominal and lower lobe lung SABR using a compression belt system

Abdominal compression (AC) is a simple and effective method of reducing diaphragmatic motion and is widely used in abdominal stereotactic ablative body radiotherapy (SABR) delivery. It is not a new method of restricting motion; however, with the increase in SABR treatments there has been much interest in adopting this technique. Furthermore, there is some evidence […]

Louise Turtle, Michelle Forshaw, Andrew Willett

The Clatterbridge Cancer Centre

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Improving patient outcomes with MR-guided daily adapted SABR for prostate cancer

In the treatment of the most common cancer in men, the MRIdian MR-linac has enabled GenesisCare to take prostate cancer radiotherapy to the next level. Dr Killian Nugent shares the results of one of the largest patient reported outcomes studies demonstrating how the innovative technology of the MRIdian MR-linac is improving the accuracy and confidence […]

Killian Nugent, Daniel Ford, Ami Sabharwal, Carla Perna, Prantik Das, Nicola Dallas, Philip Camilleri

GenesisCare UK

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Radiotherapy for liver malignancies

Liver malignancies include primary liver cancer (hepato-cellular carcinoma [HCC], cholangiocarcinoma) and liver metastases. The incidence of primary liver cancer is increasing in the UK and in the last decade the incidence rates of HCC have increased by 60% with mortality increasing at a similar pace. Surgical resection and transplantation (for HCC) are traditionally regarded as […]

Dr Maria Hawkins, Dr Sean O'Cathail

MRC Oxford Institute for Radiation Oncology, University of Oxford

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SABR in the UK: Current status and developments

Stereotactic ablative body radiotherapy (SABR), also known as stereotactic body radiotherapy (SBRT), as defined by the American Society of Radiation Oncology and the American Society of Radiology is an external beam radiation therapy method used to very precisely deliver a high dose of radiation to an extra-cranial target within the body, using either a single […]

Dr Patrick Murray, Dr Kevin Franks, Dr Pooja Jain

Leeds Teaching Hospitals NHS Trust

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Stereotactic ablative radiotherapy for lung cancer

Stereotactic ablative radiotherapy (SABR), which is also referred to as stereotactic body radiotherapy (SBRT), is defined as “the precise irradiation of an image defined extra-cranial lesion associated with the use of high radiation dose in a small number of fractions”. SABR is a relatively recent advance in the treatment of small peripheral non-small cell lung […]

Dr Brinda Sethugavalar, Dr Louise Murray, Dr Kevin Franks

Leeds Cancer Centre, St James's University Hospital

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