The human breast is an epidermal appendage derived from apocrine glands. The adult breast base overlies the second to sixth ribs in the midclavicular line and lies anterior to the deep pectoral fascia, overlying the pectoralis major muscle and the serratus anterior muscle inferolaterally. It is enclosed in a split of the superficial fascia and […]
Dr Sarah J Vinnicombe
Thirlestaine Breast Centre
Breast MRI is the most sensitive imaging test available for breast cancer detection. The fundamental breast MRI sequence is dynamic contrast-enhanced MRI (DCE-MRI), with repeated acquisition of T1-weighted (T1w) gradient echo sequences through both breasts before and after intravenous injection of gadolinium-based contrast agents. It depicts the vascularity of tissues and the morphological and kinetic […]
Dr Sarah J Vinnicombe
Gloucestershire NHS Foundation Trust; University of Dundee
While mammography and ultrasonography remain the mainstay of breast imaging, it is well recognised that each has limitations, most notably the reduced sensitivity of mammography in the dense breast, and the limited specificity of ultrasound, especially in the screening setting. Magnetic resonance imaging (MRI) of the breast is the most sensitive imaging modality for detection […]
Dr Yee Ting Sim, Dr Sarah Vinnicombe
Ninewells Hospital and Medical School