SRS

The Edinburgh Cancer Centre AVM pathway

The Scottish national service of stereotactic radiotherapy for benign conditions is based at Western General Hospital in Edinburgh. This national service began in April 2018; however, benign conditions have been treated using linac-based stereotactic radiosurgery (SRS) since 1995 in Edinburgh, initially with Radionics XKnife (Integra LifeSciences, New Jersey), until 2011 when the Novalis linac (Varian […]

Dr Paul McGrane, Ashley O'Connor

Edinburgh Cancer Centre

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Gamma Knife radiosurgery techniques

Pioneered by Lars Leksell during the 1960s, stereotactic radiosurgery (SRS) uses radiation to treat intracranial conditions through the intact skull. Early SRS focused on functional disorders and utilised protons from a synchrocyclotron, but the need for a solution better suited to routine use led Leksell to develop a dedicated device based upon narrowly-collimated photon beams […]

Gavin Wright

St James's University Hospital

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Stereotactic radiosurgery planning

Interest in stereotactic radiosurgery (SRS) and radiotherapy (SRT) techniques has increased rapidly over the last few years. There is an increasing trend to reduce fractionation regimes, with several trials reporting equivalent outcomes for reduced fractionation schedules compared with standard, long fraction courses. This increasing interest in SRS/SRT is also present for the treatment of brain […]

Colin Jennings

Rosemere Cancer Centre, Royal Preston Hospital

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Stereotactic radiosurgery for brain metastases

Brain metastases (BM) represent an increasingly common challenge in the treatment of metastatic cancer. With improvements in both systemic and intra-cranial treatment, the incidence and prevalence of BM continues to rise; the incidence of brain metastases in patients with metastatic cancer has been estimated as high as 30-40%. Historically, management of brain metastases revolved around […]

Dr Rovel Colaco

The Christie NHS Foundation Trust

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Developing a successful stereotactic service

In 1998, a stereotactic radiosurgery (SRS) service using a modified linear accelerator and fixed BrainLab headframe was established at Queen Elizabeth Hospital Birmingham (QEHB). This technique proved effective until 2010 when limitations in the service and anticipated growth led to a comprehensive review. This article outlines the steps taken to develop a higher throughput stereotactic […]

Dr Paul Sanghera, Dr Geoff Heyes, Rosemary Simmons

Queen Elizabeth Hospital

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