Scientific articles

Welcome to our scientific articles section, where we present the latest research and advancements in the field of medical imaging. This section is dedicated to providing healthcare professionals, researchers, and students with access to cutting-edge studies, innovative techniques, and comprehensive reviews. Our curated selection of scientific articles covers a wide range of topics, from diagnostic imaging and radiology to imaging technology and clinical applications. Join us in exploring the forefront of medical imaging science, staying informed about the latest discoveries, and advancing your knowledge in this dynamic field.

The changing landscape of molecular radiotherapy

Radionuclide therapy is probably the only field of medicine that allows direct imaging of a drug as it is used to treat cancer. Radioiodine was first used over 70 years ago for the treatment of benign thyroid disease and thyroid cancer. Levels of activity to administer were determined empirically, influenced largely by limitations in supply […]

Dr Glenn Flux

Royal Marsden Hospital NHS Foundation Trust

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Partial breast irradiation

Adjuvant whole breast radiotherapy after breast conserving surgery has been the standard of care in the UK for many years and has been shown to halve the risk of breast cancer recurrence and reduce the risk of breast cancer death. However, breast radiotherapy increases the risk of ischaemic heart disease and second cancers and, in […]

Dr Freddie Bartlett, Dr Anna Kirby

Queen Alexandra Hospital, The Royal Marsden Hospital

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Clinical implications of FDG PETCT in cancer of unknown primaries

Cancer of unknown primary (CUP) has an incidence of 3.3% in the UK but this is falling, largely due to improvement in diagnostics, enabling underlying pathology to be identified and treated, therefore improving survival outcomes. F-18 FDG PETCT is increasingly being used to investigate for malignancy in patients in whom initial tests have proven inconclusive […]

Emily Vaughan, Shaunak Navalkissoor

Royal Free London NHS Foundation Trust

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PET in children

The use of positron emission tomography (PET) is well-established in the management of adult tumours. However, experience in the use of PET in the paediatric population is more limited. Children are not just small adults; they differ in their psychology, normal physiology and pathophysiology. Furthermore, different tumour entities or subtypes with different biology may be […]

Ali Vahed, Leon Menezes

UCL Institute of Nuclear Medicine

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Digital radiography vs low dose 3D imaging technology: A comparison of radiation doses/image quality

The Royal National Orthopaedic Hospital (RNOH), Stanmore, is the largest orthopaedic hospital in the UK. As a centre of excellence, many of its patients undergo numerous whole spine x-rays for spinal deformity monitoring and surgical intervention. Many adolescent scoliosis patients require whole spine x-rays on a regular basis. Until recently, we have only been able […]

Antony Turner, Jane Edwards, Edmond Kinene

Royal National Orthopaedic Hospital

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Imaging of stress fractures

A stress fracture is an overuse injury in that repetitive mechanical loading of bone leads to bone damage that exceeds bone repair over time. This article refers to this type of overuse injury as opposed to an insufficiency fracture, which occurs due to normal physiological stresses on abnormal bone, commonly secondary to osteoporosis. Stress fractures […]

Dr Thomas Luff, Dr Abdul Gafoor

University Hospitals Plymouth NHS Trust

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Ultrasound-mediated targeted drug delivery in cancer patients – fact or fiction?

Despite considerable global investment towards prevention and improving outcomes, cancer remains a leading cause of morbidity and mortality worldwide; as recently as 2010, only a modest decrease (-13.8%) in standardised death rates due to cancer have been observed since 1990. In 2009 cancer cost the European Union $126 billon in healthcare cost and productivity losses […]

Paul Lyon, Prateek Katti

Institute of Biomedical Engineering, University of Oxford

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Musculoskeletal ultrasonography of the horse

Musculoskeletal disease is a major cause of morbidity and mortality in the equine population. Therefore it is important to be able to provide an accurate diagnosis with regards to advising on specific treatments, case management and prognosis. Ultrasonography has been used by the veterinary profession for musculoskeletal imaging in the horse since the 1980s, which […]

Becky Jones

B&W Equine Hospital

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