The voice of medical imaging and clinical oncology

bone

Implementation of a dual-energy CT protocol for imaging multiple myeloma

Multiple myeloma (MM) is a type of bone marrow cancer characterised by uncontrolled proliferation of malignant plasma cells in the bone marrow (BM) damaging the bones and affecting the production of healthy blood cells. MM often affects multiple parts of the body including spine, skull, pelvis and ribs. Imaging is performed for MM detection, staging, […]

Dr Ana Pascoal, Dan Hodson, Ian Honey, Olwen Westerland

Guy's and St Thomas' Hospital NHS Foundation Trust

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SPECT/CT imaging of bone

The skeleton is a metabolically active organ that undergoes continuous remodelling throughout life. Normal healthy bones are dynamic structures with inherent basal levels of turnover sustained by balanced osteoblastic and osteoclastic activity. Increased bone turnover (ie osteoblastic activity) is the central mechanism of attempts at bone healing in case of any insult, whether it is […]

Dr Zubair Ali Khan, Dr Abdul-Aziz Al-Sugair

Western General Hospital, King Faisal Specialist Hospital and Research Centre

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MR-guided HIFU for pain palliation of bone metastases

A new clinical multi-centre trial is underway to assess the effectiveness of pain palliation in bone metastases using the Philips Sonalleve MR-HIFU (high intensity focused ultrasound) system. Researchers at The Royal Marsden and The Institute of Cancer Research (ICR), London, are participating in the trial and this article outlines the clinical context and our experience […]

Sharon Giles

The Royal Marsden Hospital

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MR imaging of bone and joint infection

Evaluation of suspected bone and joint infection is a common conundrum and radiology plays a vital role in not only ascertaining the presence of infection but also to assess the associated complications.

Dr Abhishek Jain, Dr Hifz Aniq

Royal Liverpool University Hospital

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Radionuclide bone SPECT/CT in orthopaedics

Radionuclide 99mTc-MDP planar bone scan is the most commonly performed nuclear medicine procedure and may aid diagnosis of benign and malignant bone pathologies. 99mTc-MDP is injected intravenously and subsequently taken up by osteoblasts and incorporated into the bone matrix. In the process it acts as a marker for new bone formation, bone turnover and local […]

Dr Kanhaiyalal Agrawal, Dr Alexis Corrigan, Dr Sanjay Vijaynathan, Dr Gopinath Gnanasegaran

Guy's and St Thomas' Hospital NHS Foundation Trust

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Radionuclide SPECT/CT in oncology

Radionuclide imaging employs radiolabelled tracers in the investigation of suspected cancer, subsequent staging, response assessment and the assessment of recurrence. Highly specific tracers, that target cellular receptors and metabolic pathways, are used in investigating patients with known or suspected cancers. Radionuclide imaging techniques have superior sensitivity compared to anatomic techniques and provide functional/metabolic information. However […]

Dr Gopinanth Gnanasegaran, Dr Alexis Corrigan, Christopher Sibley-Allen, Dr Kanhaiyalal Agrawal

Guy's and St Thomas' Hospital NHS Foundation Trust

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