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molecular radiotherapy

Dosimetry to improve molecular radiotherapy outcomes

This article explores the critical role of dosimetry in enhancing outcomes for molecular radiotherapy (MRT), a treatment modality that delivers targeted radiation to cancer cells via radiopharmaceuticals. While MRT has grown significantly in the UK over the past two decades, current prescribing practices often rely on fixed activity or weight-based adjustments, which fail to account […]

Matt Aldridge

Dr Matt Aldridge

King's College Hospital, London; Internal Dosimetry User Group

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The role of the consultant radiographer in molecular radiotherapy

The decision by departments and NHS trusts/boards to identify service requirements for consultant radiographers in molecular radiotherapy (MRT) is essential. Service needs should be patient centred, and the creation of a consultant radiographer post must be driven by the intention to offer the highest standards of patient care and to improve the patient care pathway, […]

Jo Weekes

New Cross Hospital

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Improving target volume delineation for 3D image-based dosimetry in PRRT

Peptide receptor radionuclide therapy (PRRT) using radiolabelled somatostatin analogues is currently the most effective molecular radiotherapy (MRT) treatment for patients who suffer from neuroendocrine tumours (NET) with metastasised disease. In PRRT the treatment is systemic and the most frequent treatment protocol is to administer 7.4GBq of Lu-177 up to four times with a six to […]

Dr Emiliano Spezi, Dr Salvatore Berenato

Cardiff University, Velindre Cancer Centre

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The future of molecular radiotherapy

Molecular radiotherapy (MRT) refers to treatment that delivers radiation to a tissue via the interaction of a radiopharmaceutical with a molecular receptor, although is used in a more general sense to refer to any treatment with radiotherapeutics that can take account of imaging and patient dosimetry. Probably the most well-known example of MRT is the […]

Professor Jon Wadsley, Dr Glenn Flux

Weston Park Cancer Centre, Royal Marsden Hospital

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