molecular

Molecular imaging using IgG-TAT based radioimmunoconjugates

Clinical imaging has become a fundamental tool in modern medicine, utilising modalities including CT, MRI, ultrasound, SPECT and PET. The ever-increasing complexity revealed by molecular biology along with the implementation of highly specialised precision therapeutics has created a demand for molecularly targeted imaging devices, also known as molecular imaging.

Mathew Veal, Professor Bart Cornelissen

University of Oxford, University Medical Centre Groningen

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The changing landscape of molecular radiotherapy

Radionuclide therapy is probably the only field of medicine that allows direct imaging of a drug as it is used to treat cancer. Radioiodine was first used over 70 years ago for the treatment of benign thyroid disease and thyroid cancer. Levels of activity to administer were determined empirically, influenced largely by limitations in supply […]

Dr Glenn Flux

Royal Marsden Hospital NHS Foundation Trust

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Newer radionuclide therapies

Radionuclide therapy (RNT), also known as molecular radiotherapy (MRT), utilises unsealed ionising radiation to target particular tissues. RNT depends on the properties of the radionuclides and tracer conjugates that selectively binds to cell receptors. The majority of radionuclides used in RNT are beta (β)-particles, although there is an established role and also emerging applications using […]

Dr Francis Sundram, Dr Eleonora Manca

University Hospital Southampton NHS Foundation Trust

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