The voice of medical imaging and clinical oncology

pancreas

Advances in radiotherapy delivery in hepatobiliary and pancreatic malignancies

The role of targeted radiotherapy in patients with locally advanced pancreatic cancer (LAPC) is constantly evolving. While there is uniform agreement across guidelines that patients with good performance status should receive chemotherapy as their first line of treatment, there is no consensus on how to manage patients with localised disease who do not have sufficient […]

Hannah Harford-Wright, Marina Khan, Kasia Owczarczyk

GenesisCare UK; Guy's and St Thomas' NHS Foundation Trust

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MRI of pancreatic cystic lesions

Pancreatic cystic lesions (PCL) are common, demonstrated on MRI in up to 49% of the healthy population in one prospective series. They are mostly incidentally detected lesions. Characterising PCLs is important as, while most are benign, some lesions have malignant potential and may require surveillance, endoscopic ultrasound (EUS) with fine needle aspiration (FNA), and occasionally […]

Dr Tobi Meadows, Sadiq Usman, Jennifer Newman, Dr Joshua Shur

Royal Marsden Hospital NHS Foundation Trust

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Normal pancreatic appearances of 68Ga-DOTA

Neuroendocrine tumours (NET) arise from the malignant growth of neuroendocrine cells, a system of paracrine cells distributed throughout the body. Most NETs arise from the gastrointestinal tract, most commonly in the small bowel and the lungs. About half of NETs occur in the small bowel and about one quarter in the lungs. Other forms of […]

Dr Guglielmo La Torre, Dr Simon Hughes

University Hospitals Birmingham NHS Foundation Trust

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Acute pancreatitis

Acute pancreatitis is acute inflammation of the pancreas, typically presenting with acute onset epigastric pain and often radiating to the back. Hans Chiari was the first to propose autodigestion of the exocrine pancreatic tissue by the premature activation of digestive enzymes as the underlying pathophysiology of pancreatitis. This activation of enzymes results in breakdown of […]

Dr Myriam Guessoum / Dr Nirav Patel

St George's University Hospitals NHS Trust

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Therapeutic ultrasound: a new tool in the treatment of pancreatic cancer

Ultrasound energy propagates as a pressure wave (sound) emitted at a frequency above that of the upper threshold for human hearing. Diagnostic ultrasound scanners have found widespread use in imaging applications where they offer a real-time, non-invasive and non-ionising method of detecting tissues and structures. The premise here is that diagnostic ultrasound, especially as used […]

Dr Petros Mouratidis, Professor Gail ter Haar

The Institute of Cancer Research

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Ultrasound in the investigation of the pancreas and the biliary tree

Ultrasound (US) is a central imaging tool in the investigation of pancreaticobiliary problems. This article explores common clinical scenarios and the role US plays in patient care. In particular, we will consider how the strengths and weaknesses of US impact on its place in the pathway. US is capable of detailing anatomy and pathology in […]

Dr Tim Hoare, Dr Andy McNeill

Newcastle upon Tyne Hospitals NHS Foundation Trust

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