preclinical

Ultrasound in translational research – of mice and men

Ultrasound imaging applied to preclinical animal models provides unique insights into the development and mechanisms of many clinical diseases. The sequencing of the mouse genome and the resultant ability to be able to modify the genetic footprint of these small animals, coupled with their short gestation periods and high reproduction rates, make them the model […]

Professor Carmel Moran

University of Edinburgh

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Improving the application of PET to radiotherapy via preclinical research: Status and potential

Currently, radiotherapy is prescribed assuming homogeneous response to therapy across the patient population. Improving its efficacy is most likely to be achieved by personalisation to the individual patient. This can be achieved by improving target delineation for dose escalation, reducing toxicity, hypofractionation and dose painting approaches, as well as selecting patients via genomic or imaging […]

Dr Chris Cawthorne, Dr Stephen Maher, Dr Najeeb Ahmed, Professor Andrew Beavis

University of Hull, Castle Hill Hospital NHS Trust

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