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SPECT/CT

Hepatobiliary scintigraphy in clinical practice: a protocol-driven approach at King’s College Hospital, London

Hepatobiliary scintigraphy, widely known as the HIDA scan, remains an indispensable functional imaging tool for the assessment of hepatocyte function, biliary patency and gallbladder contractility. Despite the maturity of the technique, day-to-day delivery is anything but uniform: the same radiopharmaceutical is asked to answer very different clinical questions, from suspected acute cholecystitis and biliary dyskinesia […]

Marisa Cruz

Marisa Botelho Cruz, Rosalind Pliszka, A Michael Peters

King’s College Hospital, London

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An overview of CZT technology

The gamma camera has been a stalwart of nuclear medicine for many years. First described in 1958 by Hal Anger, the gamma camera is still the most used instrument for nuclear medicine imaging studies. While the transition to rotating tomographic SPECT systems and the incorporation of CT for SPECT attenuation correction and localisation has changed […]

Professor John C Dickson

University College London Hospitals NHS Foundation Trust

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SPECT/CT for foot and ankle pathologies

Foot and ankle injuries are common, chronic pain is prevalent and many patients present with symptoms that cannot be fully explained by conventional imaging techniques. This article will explore the increasing role of SPECT/CT in the investigation of common foot and ankle pathologies. Conventional diagnostic techniques such as plain radiography, ultrasound, CT and MRI currently […]

Dr Luke Zhu, Dr Malavika Nathan

West Midlands Deanery; Royal Free London NHS Foundation Trust

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Review of incidental findings in whole body oncology SPECT/CT

The national and global impact of cancer is an important consideration for healthcare services worldwide. In the UK, over half of adults under 65 years of age will be diagnosed with cancer at some point in their lifetime. Bone metastases can contribute greatly to cancer morbidity with complications such as bone pain, hypercalcaemia, pathological fractures […]

Dr Hend Komber, Dr Rob Foley, Dr Stewart Redman, Professor Richard Graham, Dr David Little

Royal United Hospitals Bath NHS Foundation Trust

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Can nuclear medicine help with a rising PSA post radical treatment?

Nuclear medicine imaging has always played an important role in the management of patients with prostate cancer, both pre and post therapy. This has primarily been through the use of conventional gamma camera imaging and bone scans for the detection of metastatic bone disease for which prostate cancer has a predilection. The role of nuclear […]

Dr Brent Drake, Dr Thomas Gruning, Dr Peter Sankey, Dr Asha Omar

The Royal Marsden Hospital; Derriford Hospital; University Hospitals Plymouth NHS Trust

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SPECT/CT in lower back pain

SPECT/CT can be performed to help evaluate potential causes of lower back pain. It can be used as a problem-solver where other imaging techniques have not provided a diagnosis, or to answer a specific question such as localisation of a site of primary pain generation. Single photon emission computed tomography (SPECT) has a better contrast […]

Dr James Howard

Manchester University NHS Foundation Trust

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Clinical applications of SPECT/CT

SPECT/CT has established itself as a powerful diagnostic tool in nuclear medicine. The combined advantages of high sensitivity SPECT imaging with high specificity CT imaging has been shown to be superior to planar and SPECT imaging for many clinical indications. The CT component of SPECT/CT improves image quality through attenuation correction (AC), precise anatomical localisation […]

Dr Malavika Nathan

Royal Free London NHS Foundation Trust

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SPECT/CT in oncology

Radionuclide imaging can demonstrate whole body functional/metabolic information and plays an important role in oncology clinical and research practice. It is integral to many clinical pathways, assisting in diagnosis and staging, pre-operative localisation, monitoring response and detecting recurrence. However, planar scintigraphy and SPECT lack anatomical and structural details resulting in low specificity and sensitivity with […]

Dr Fraser Hendry, Dr Sai Han

Glasgow Royal Infirmary, Gartnavel General Hospital

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