123I-Ioflupane progression studies – avoiding pitfalls

Author(s): Dr Alp Notghi, Mr Joseph O'Brien

Hospital: City Hospital

Reference: RAD Magazine, 49, 580, 17-18


Ioflupane (DaTSCAN) is a well established diagnostic tool for diagnosis of Parkinson’s disease (PD), as well as dementia with Lewy bodies (DLB). Ioflupane binds to the dopamine active transporters in the presynaptic membrane of the dopaminergic nerve terminals (DNT). Dopaminergic pathways in the brain are involved in various brain functions. Degeneration of dopaminergic neurons in […]

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