The voice of medical imaging and clinical oncology

SPECT

Can nuclear medicine help with a rising PSA post radical treatment?

Nuclear medicine imaging has always played an important role in the management of patients with prostate cancer, both pre and post therapy. This has primarily been through the use of conventional gamma camera imaging and bone scans for the detection of metastatic bone disease for which prostate cancer has a predilection. The role of nuclear […]

Dr Brent Drake, Dr Thomas Gruning, Dr Peter Sankey, Dr Asha Omar

The Royal Marsden Hospital; Derriford Hospital; University Hospitals Plymouth NHS Trust

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Assessment of the effect of cardiac contraction on SPECT myocardial perfusion imaging

SPECT myocardial perfusion imaging (MPI) is one of the most common nuclear medicine procedures undertaken in the UK with over 80,000 performed per year. It is used for managing cardiovascular disease, which often presents as angina and can lead to myocardial infarction (MI). 99mTc SPECT MPI is non-invasive nuclear medicine imaging that provides functional information […]

Stephanie Jewitt, Dr Sarah Cade, Martyn Evans

Oxford University Hospitals NHS Trust, Royal United Hospitals Bath NHS Trust

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Defining the future of quantitative SPECT/CT

Single photon emission tomography computed tomography (SPECT/CT) imaging, with its innate ability to detect and characterise abnormalities in their earliest forms, can be a meaningful tool for determining prompt diagnoses and developing personalised treatment strategies. Such a tool is invaluable as we move towards precision medicine, and the significant addition of reliable quantitative measurements only […]

Stefan Voo, James Ross, Sabina Dizdarevic, John Dickson

University College London Hospitals NHS Trust, Brighton and Sussex University Hospitals NHS Trust

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Clinical applications of paediatric SPECT/CT

SPECT/CT is now an established diagnostic imaging technology considered as a standard of care within paediatric imaging. Although the majority of the published literature that supports the use of hybrid imaging is within the adult domain, SPECT/CT can be utilised with success within the paediatric population in specific contexts where sufficient evidence exists for an […]

Ben Thurlow, Lorenzo Biassoni

Great Ormond Street Hospital for Sick Children NHS Foundation Trust

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Imaging of spinal fusion

Surgical spinal fusion is a procedure where two or more of the vertebrae of the spine are “fused” together in an attempt to achieve solid arthrodesis and to potentially eliminate painful movement or to correct deformity. The purpose of the spinal hardware is to provide additional spinal stability while helping the fusion set up. The […]

Dr Luigi Pedone, Dr Ian Pressney

Fundation Policlinico Agostino Gemelli, Royal National Orthopaedic Hospital

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Current applications and controversies in bone SPECT/CT imaging

Bone scintigraphy is the largest single volume area in nuclear medicine, while PETCT is a close second. Most bone imaging is planar imaging for oncology. Bone SPECT/CT is a dual modality imaging test that has not gained as high a profile as other nuclear medicine techniques such as PETCT, despite recent significant advances in both […]

Dr Emma Stanley, Jack O'Shea, Hilary McKeown, Donagh O'Sullivan, Dr Martin O'Connell

Mater Misericordiae University Hospital

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Radionuclide imaging in epilepsy

Epilepsy is one of the most frequent chronic neurological disorders, with an incidence of 50/100,000/year and a prevalence of 0.5-1% in Western society. One third of patients with epilepsy have seizures that do not respond to medical treatment leading to cognitive decline, poor quality of life, high societal costs and significantly increased mortality including sudden […]

Dr Maria Vittoria Mattoli, Dr Francesco Fraioli, Dr Beate Diehl

University College London Hospitals NHS Foundation Trust, Universita Cattolica del Sacro Cuore, University College London

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